IncRNA MVIH correlates with disease features, predicts treatment response and survival in pediatric acute myeloid leukemia
نویسندگان
چکیده
منابع مشابه
Pediatric Acute Myeloid Leukemia
Acute leukemias are clonal diseases characterized by a maturation arrest and by enhanced proliferation of hematopoietic precursor cells, which normally would differentiate into mature blood cells. The leukemic cells are released from the bone marrow into the peripheral blood and may accumulate in vital organs such as the spleen, liver, skin, central nervous system and lymph nodes. Chronic leuke...
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Few data are available about hydatid cysts in patients with malignancy; however, these have rarely been described in association with leukemia. The purpose of this report was to present an unusual case of coexisting leukemia and pulmonary hydatid cysts.This study presented a 13-year-old boy with acute myeloid leukemia who was diagnosed with bilateral pulmonary hydatid cysts after the completion...
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Background: Acute Myeloid Leukemia (AML) with translocation (3,3) is a form of AML that may present de novo or may arise from a previous myelodysplastic syndrome. It is often associated with normal or elevated peripheral blood platelet count and increased bone marrow megakaryocytes with associated multi lineage dysplasia. A subset of patients present with hepatosplenomegaly while a few cases h...
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Acute lymphoblast leukemia (ALL) is characterized by overproduction of immature white blood cells in the bone marrow. ALL is most common in the childhood and has high (>80%) cure rate. In contrast, acute myeloid leukemia (AML) has far greater mortality rate than the ALL and is most commonly affecting older adults. However, AML is a leading cause of childhood cancer mortality. In this study, we ...
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Gene signatures have been associated with outcome in pediatric acute lymphoblastic leukemia (ALL) and other malignancies. However, determining the molecular drivers of these expression changes remains challenging. In ALL blasts, the p53 tumor suppressor is the primary regulator of the apoptotic response to genotoxic chemotherapy, which is predictive of outcome. Consequently, we hypothesized tha...
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ژورنال
عنوان ژورنال: Journal of Clinical Laboratory Analysis
سال: 2021
ISSN: 0887-8013,1098-2825
DOI: 10.1002/jcla.23739